SCHEMBL11339062

SCHEMBL11339062

C(=Cc1ccccc1)C=Nc1cccc(N=CC=Cc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C19 P33261 1/20 0.58
MAOB P27338 2/20 0.50
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
KDM4E B2RXH2 3/20 0.44
BLM P54132 1/20 0.44
TRPA1 O75762 1/20 0.43
LMNA P02545 1/20 0.43
ALOX5 P09917 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 4/20 0.42
MAPT P10636 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11339061 1.00 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL11339066 1.00 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL1877894 0.90 MAOB (0.56) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL2024202 0.90 MAOB (0.56) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL14196500 0.90 MAOB (0.56) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL28486791 0.88 KMT2A (0.51) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL11590991 0.85 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL13636686 0.80 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL28766487 0.77 ALDH1A1 (0.51) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB
SCHEMBL30379657 0.77 ALDH1A1 (0.51) ALDH1A1CYP1A2CYP3A4CYP2C19MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4268603-A Photoresist compositions TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US claimed
US-4268603-A Photoresist compositions TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US disclosed