Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345366 | 0.80 | CYP3A4 (0.47) | TSHRGAACYP3A4 | |
| SCHEMBL15011501 | 0.80 | TSHR (0.48) | POLBPPARDTSHRGAACYP3A4 | |
| SCHEMBL27268583 | 0.77 | TSHR (0.42) | POLBPPARDTSHRGAACYP3A4 | |
| SCHEMBL11348244 | 0.77 | GABBR2 (0.37) | CYP2C19TDP1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL14495223 | 0.77 | TSHR (0.46) | POLBPPARDTSHRGAACYP3A4 | |
| SCHEMBL8549163 | 0.75 | TSHR (0.43) | POLBPPARDTSHRGAACYP3A4 | |
| SCHEMBL9162193 | 0.75 | TSHR (0.43) | POLBPPARDTSHRGAACYP3A4 | |
| SCHEMBL10437673 | 0.73 | GABBR2 (0.44) | TDP1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL624045 | 0.73 | GABBR2 (0.44) | TDP1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL7298542 | 0.73 | TSHR (0.42) | POLBPPARDTSHRGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246103-A | INHIBIT PRECIPITATION OF HARD WATER IONS ESPECIALLY FOR INDUSTRIAL WATER AND SLUDGE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |