SCHEMBL11339663

SCHEMBL11339663

CC1C(OC(=O)c2cc(C(=O)OC3CCN(C)C(C)(C)C3C)c(C(=O)OC3CCN(C)C(C)(C)C3C)cc2C(=O)OC2CCN(C)C(C)(C)C2C)CCN(C)C1(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35
SCN1A P35498 4/20 0.33
SCN2A Q99250 4/20 0.33
SCN3A Q9NY46 4/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
NR1I2 O75469 1/20 0.31
HTR3B O95264 1/20 0.31
HTR3A P46098 1/20 0.31
HTR3D Q70Z44 1/20 0.31
HTR3C Q8WXA8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886937 0.81 CYP2D6 (0.30) CYP2D6CYP2C19
SCHEMBL28886947 0.81 CYP2D6 (0.30) CYP2D6CYP2C19
Water SCHEMBL28999761 0.81 MEN1 (0.50) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL7148667 0.80 CHRM2 (0.42) MEN1KMT2ACYP2D6CYP2C19
SCHEMBL28886953 0.79 OPRD1 (0.32) SCN1ASCN2ASCN3A
SCHEMBL1433609 0.78 SCN1A (0.41) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL29094119 0.73
SCHEMBL28886925 0.73 EPHX1 (0.46)
SCHEMBL28886927 0.73 CYP19A1 (0.42)
SCHEMBL7473867 0.72 CYP2D6 (0.31) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299926-A STERICALLY HINDERED POLYALKYLPIPERIDINE CIBA-GEIGY CORPORATION (US) 1981-11-10 US disclosed
US-4260689-A PIPERIDONE-CONTAINING POLYAMINES CIBA-GEIGY CORPORATION (US) 1981-04-07 US disclosed
US-4260691-A POLYURETHANES WITH PIPERIDINE-CONTAINING MONOMERS CIBA-GEIGY CORPORATION (US) 1981-04-07 US disclosed
US-4250268-A Polysilylesters having a polyalkylpiperidine as part of the polymer useful as light stabilizers for plastics CIBA-GEIGY CORPORATION (US) 1981-02-10 US disclosed
US-4234700-A POLYCARBONATE OR POLYUREA CONTAINING POLYALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4234699-A POLYETHERS CONTAINING POLYALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4233412-A POLYESTERS CONTAINING STERICALLY HINDERED ALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4233410-A STERICALLY HINDERED POLYUREAS OF LOW MOLECULAR WEIGHT CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4232131-A POLYAMIDE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed