Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340988 | 0.96 | MAPT (0.65) | MAPTKMT2AMEN1GAAABCB1 | |
| SCHEMBL11338530 | 0.95 | KMT2A (0.66) | MAPTKMT2AMEN1GAAABCB1 | |
| SCHEMBL11363338 | 0.95 | KMT2A (0.66) | MAPTKMT2AMEN1GAAABCB1 | |
| SCHEMBL11363647 | 0.92 | KMT2A (0.67) | MAPTKMT2AMEN1GAAABCB1 | |
| SCHEMBL11341153 | 0.92 | KMT2A (0.67) | MAPTKMT2AMEN1GAAABCB1 | |
| SCHEMBL30173476 | 0.85 | TSHR (0.78) | MAPTKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL3805742 | 0.85 | TSHR (0.78) | MAPTKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL11337833 | 0.84 | ALDH1A1 (0.67) | KMT2AMEN1GAAABCB1TSHR | |
| SCHEMBL5515133 | 0.84 | ALDH1A1 (0.79) | MAPTKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL9636466 | 0.84 | ALDH1A1 (0.79) | MAPTKMT2AMEN1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298603-A | LOCAL ANESTHETICS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-11-03 | — | — | US | disclosed |
| EP-0031632-A1 | O-Aminoalkylsalicylates, process for their preparation, and their pharmaceutical compositions | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-07-08 | — | — | EP | disclosed |