Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340700 | 1.00 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11323438 | 0.86 | ALDH1A1 (0.62) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11323440 | 0.86 | ALDH1A1 (0.62) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11330911 | 0.85 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11324833 | 0.81 | NPC1 (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11324863 | 0.81 | NPC1 (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL1332207 | 0.77 | KDM4E (0.64) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6327826 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11331816 | 0.76 | KMT2A (0.71) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11335672 | 0.76 | KMT2A (0.60) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252952-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |
| US-4178445-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| US-4039536-A | 7-(α-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACIDS AND THEIR DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-08-02 | — | — | US | disclosed |