⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487175 | 0.82 | PTGS1 (0.35) | — | |
| SCHEMBL9155297 | 0.79 | — | — | |
| SCHEMBL9122682 | 0.78 | — | — | |
| SCHEMBL20642065 | 0.75 | CNR1 (0.32) | — | |
| SCHEMBL11491618 | 0.72 | — | — | |
| SCHEMBL588998 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL15489686 | 0.68 | — | — | |
| SCHEMBL11694972 | 0.67 | — | — | |
| SCHEMBL16527269 | 0.67 | KMT2A (0.33) | — | |
| SCHEMBL18935685 | 0.67 | GNAI3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263434-A | UV STABILIZERS FOR POLYMERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1981-04-21 | — | — | US | disclosed |
| US-4108829-A | PHOTOSTABILITY | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-08-22 | — | — | US | disclosed |
| US-4086204-A | LIGHT STABILIZERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-04-25 | — | — | US | disclosed |
| US-4086207-A | REACTING A DIAMINE WITH CARBONYL CHLORIDE OR A DIISOCYANATE | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-04-25 | — | — | US | disclosed |