SCHEMBL11342000

SCHEMBL11342000

CC=C(C(=O)O)c1c([N+](=O)[O-])cc(C(C)CCCCCC)cc1[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
MAPT P10636 3/20 0.36
GAA P10253 1/20 0.36
HCAR3 P49019 3/20 0.36
PTGS2 P35354 1/20 0.36
PLA2G4B P0C869 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
PLK1 P53350 1/20 0.33
PLK3 Q9H4B4 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341938 1.00 ESR1 (0.37) ESR1MAPTGAAHCAR3PTGS2
SCHEMBL11057818 0.86 NR1I2 (0.37) ESR1MAPTGAAHCAR3PTGS2
SCHEMBL11057808 0.86 NR1I2 (0.37) ESR1MAPTGAAHCAR3PTGS2
SCHEMBL11064694 0.85 TDP1 (0.41) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL19328778 0.85 TDP1 (0.41) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL8754555 0.85 TDP1 (0.41) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL8754550 0.85 TDP1 (0.41) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL11058378 0.82 MAPT (0.39) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL11058372 0.82 MAPT (0.39) ESR1MAPTGAAHCAR3ALDH1A1
SCHEMBL674435 0.80 GPR84 (0.47) ESR1MAPTGAAHCAR3PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4282168-A FUNGICIDES PPG INDUSTRIES, INC. (US) 1981-08-04 US disclosed
US-4213915-A FUNGICIDES, NEMATOCIDES PPG INDUSTRIES, INC. (US) 1980-07-22 US disclosed
US-4132800-A NEMATOCIDES FOR PLANTS PPG INDUSTRIES, INC. (US) 1979-01-02 US disclosed
US-4132801-A Control of plant fungi with S-p-methoxyphenyl N-2,3-dibromopropylthiolcarbamate PPG INDUSTRIES, INC. (US) 1979-01-02 US disclosed
US-4120886-A APHIDICIDES PPG INDUSTRIES, INC. (US) 1978-10-17 US disclosed
US-4117155-A APPLYING FUNGICIDE TO SOIL PPG INDUSTRIES, INC. (US) 1978-09-26 US disclosed
US-4075006-A PESTICIDES, NEMATOCIDES, FUNGICIDES PPG INDUSTRIES, INC. (US) 1978-02-21 US disclosed
US-4059609-A HERBICIDE, NEMATOCIDE, FUNGICIDE PPG INDUSTRIES, INC. (US) 1977-11-22 US disclosed
US-4056549-A PLANT PESTICIDE PPG INDUSTRIES, INC. (US) 1977-11-01 US disclosed
US-4055657-A S-ARYL-N-ALKYL-THIOLCARBAMATES PPG INDUSTRIES, INC. (US) 1977-10-25 US disclosed
US-4055656-A S-ARYL-N-CYCLOALKYLTHIOLCARBAMATES PPG INDUSTRIES, INC. (US) 1977-10-25 US disclosed
US-4046912-A S-p-Methoxyphenyl N-2,3-dibromopropylthiolcarbamate and its use in the control of plant nematodes PPG INDUSTRIES, INC. (US) 1977-09-06 US disclosed