Naphthalene

Naphthalene

SCHEMBL11342178

Oc1ccc(-c2ccc(O)cc2)cc1.c1ccc2ccccc2c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.76
ESR2 Q92731 7/20 0.76
MMP3 P08254 1/20 0.72
BCL2L1 Q07817 1/20 0.72
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP1A2 P05177 1/20 0.57
ABL1 P00519 1/20 0.52
ABCB1 P08183 1/20 0.52
BCR P11274 1/20 0.52
MAPT P10636 2/20 0.52
HSD17B1 P14061 2/20 0.52
HSD17B2 P37059 2/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
LMNA P02545 1/20 0.52
RAB9A P51151 1/20 0.52
AR P10275 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL27305592 0.90 CYP1A2 (0.67) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL234529 0.87 ESR1 (1.00) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL29672355 0.87 ESR1 (1.00) ESR1ESR2MMP3BCL2L1MEN1
Biphenyl SCHEMBL28693245 0.85 MMP3 (0.68) ESR1ESR2MMP3BCL2L1MEN1
Phenol SCHEMBL7098665 0.84 MMP3 (0.88) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL11645258 0.84 MMP3 (1.00) ESR1ESR2MMP3BCL2L1MEN1
Biphenyl SCHEMBL9955402 0.84 MMP3 (1.00) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL38273 0.84 MMP3 (1.00) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL4236248 0.84 MMP3 (1.00) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL7865208 0.84 MMP3 (1.00) ESR1ESR2MMP3BCL2L1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0033011-A1 Polyarylate blends with polyetherimides UNION CARBIDE CORPORATION (US) 1981-08-05 EP disclosed
US-4250279-A MOLDING MATERIALS UNION CARBIDE CORPORATION (US) 1981-02-10 US disclosed