Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.55 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805463 | 0.79 | ACE (0.69) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL498453 | 0.74 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL4838500 | 0.74 | MME (0.65) | MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL7054010 | 0.72 | MME (0.62) | MMEACECPA1ACE2 | |
| SCHEMBL3411005 | 0.72 | MME (0.58) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL28526383 | 0.72 | MME (0.55) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10925267 | 0.71 | MMP2 (0.59) | MMESLC15A1 | |
| SCHEMBL25432477 | 0.71 | EPHX1 (0.58) | MMEACEALDH1A1CPA1ACE2 | |
| SCHEMBL8240623 | 0.71 | EPHX1 (0.58) | MMEACEALDH1A1CPA1ACE2 | |
| SCHEMBL2456064 | 0.71 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038758-A1 | Amino-acids derivatives and their therapeutic use | SOCIETE CIVILE BIOPROJET (FR) | 1981-10-28 | — | — | EP | disclosed |