Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392684 | 0.91 | RIPK1 (0.53) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11356456 | 0.90 | RIPK1 (0.54) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11393696 | 0.90 | RIPK1 (0.49) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11388457 | 0.89 | RIPK1 (0.51) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11353375 | 0.89 | RIPK1 (0.53) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11346521 | 0.88 | RIPK1 (0.52) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11393693 | 0.87 | RIPK1 (0.49) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL11388277 | 0.87 | RIPK1 (0.51) | KMT2ARIPK1MAPTAPPCASP1 | |
| SCHEMBL10756366 | 0.87 | RIPK1 (0.61) | KMT2ARIPK1ALDH1A1MAPK1MEN1 | |
| SCHEMBL11391965 | 0.87 | MAPK1 (0.70) | RIPK1KDM4EALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037134-A1 | Pyridazine derivatives, process for their preparation, compositions containing them and methods of regulating the growth of plants, increasing the yield of soya bean plants and sterilizing the male anthers of plants, including small grain cereal plants, using them as well as a method of producing F1 hybrid seed | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-10-07 | — | — | EP | disclosed |
| EP-0025498-A2 | Process for the preparation of pyridazine derivatives | ROHM AND HAAS COMPANY (US) | 1981-03-25 | — | — | EP | disclosed |