Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759348 | 0.90 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18139779 | 0.89 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18139085 | 0.89 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18140763 | 0.89 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18139561 | 0.89 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| 1,6-Hexanediol SCHEMBL8740541 | 0.88 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL341500 | 0.88 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL37007 | 0.88 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| 1,6-Hexanediol SCHEMBL18725299 | 0.88 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3504159 | 0.88 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255196-A | A CURABLE DILUENT DESCRIBED AS THE MIXED ESTERS OF A POLYOL WITH MIXED NATURAL DRYING OIL FATTY ACIDS AND AN UNSATURATED ACYCLIC ACID | ROHM AND HAAS COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4253397-A | COMPRISING A CURABLE LIQUID REACTIVE DILUENT WHICH IS A POLYUNSATURATED ESTER | ROHM AND HAAS COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| EP-0015147-A1 | Lithographic ink containing oxidatively curable reactive diluent and use thereof | ROHM AND HAAS COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |