SCHEMBL1759348

SCHEMBL1759348

C=C(C)C(=O)OCCCC(O)CCCO

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 4/20 0.35
PTPN1 P18031 1/20 0.34
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344293 0.90 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL275389 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4528593 0.86 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28065743 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28224640 0.86 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28204149 0.85 TSHR (0.69) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1133357 0.84 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28049824 0.84 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8965903 0.84 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8084375 0.84 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120288700-A1 COATING COMPOSITION BYK-CHEMIE GMBH (DE) 2012-11-15 US disclosed
EP-2499206-A1 COATING COMPOSITION BYK-Chemie GmbH (DE) 2012-09-19 EP disclosed
WO-2011060050-A1 COATING COMPOSITION BYK-CHEMIE GMBH (DE) 2011-05-19 WO disclosed
EP-0832947-B1 Scratch resistant clearcoats containing surface reactive microparticles and method therefor BASF CORP (US) 2003-05-14 EP disclosed
US-5853809-A Scratch resistant clearcoats containing suface reactive microparticles and method therefore BASF CORPORATION (US) 1998-12-29 US disclosed
EP-0832947-A2 Scratch resistant clearcoats containing surface reactive microparticles and method therefor BASF CORPORATION (US) 1998-04-01 EP disclosed
US-5548016-A BLEND OF ACRYLIC AND POLYURETHANE POLYMERS TREMCO, INC. (US) 1996-08-20 US disclosed
EP-0391166-B2 Chip resistant coatings and methods for application PPG INDUSTRIES INC (US) 1996-07-03 EP disclosed
EP-0139187-B2 COLOR PLUS CLEAR COATING SYSTEM UTILIZING INORGANIC MICROPARTICLES PPG INDUSTRIES, INC. (US) 1992-01-22 EP disclosed
US-5066733-A Polyurethane Coatings In Automobiles PPG INDUSTRIES, INC. (US) 1991-11-19 US disclosed
US-4680204-A Color plus clear coating system utilizing inorganic microparticles PPG INDUSTRIES, INC. (US) 1987-07-14 US disclosed
US-4677004-A MULTILAYER-PIGMENT CONTAINING UNDERCOATING AND TRANSPARENT OV ERCOATING PPG INDUSTRIES, INC. (US) 1987-06-30 US disclosed
US-4652470-A SILICA IN BASECOAT PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
US-4620994-A Color plus clear coating system utilizing organo-modified clay PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4620993-A Color plus clear coating system utilizing organo-modified clay in combination with organic polymer microparticles PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4558075-A CROSSLINKABLE RESIN BINDER, SOLVENT SYSTEM, AND CLAY DISPERSED THEREIN PPG INDUSTRIES, INC. (US) 1985-12-10 US disclosed
US-4526910-A Film forming binder comprising crosslinkable resin, microparticles dispersed therein, solvent PPG INDUSTRIES, INC. (US) 1985-07-02 US disclosed
US-4522958-A High-solids coating composition for improved rheology control containing chemically modified inorganic microparticles PPG INDUSTRIES, INC. (US) 1985-06-11 US disclosed
EP-0139187-A1 Color plus clear coating system utilizing inorganic microparticles PPG INDUSTRIES, INC. (US) 1985-05-02 EP disclosed
US-4293398-A Process for cathodically electrodepositing polymers having tertiary amine oxide groups PPG INDUSTRIES, INC. (US) 1981-10-06 US disclosed