Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | UBE2N | P61088 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508500 | 0.88 | MEN1 (0.54) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL10716434 | 0.81 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL8083289 | 0.80 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL11472815 | 0.79 | MEN1 (0.47) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL13081865 | 0.79 | SMN1; SMN2 (0.68) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL9340133 | 0.79 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL11556828 | 0.79 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL10879156 | 0.79 | ALDH1A1 (0.56) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL10879145 | 0.78 | MEN1 (0.55) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 | |
| SCHEMBL9472399 | 0.78 | KMT2A (0.55) | KMT2ASMN1; SMN2MEN1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284704-A | Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt | EASTMAN KODAK COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| US-RE30267-E | SEMIPERMEABLE MEMBRANE, THIN FILM | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-4066403-A | DECOMPOSITION, PERMEABLE BARRIERS | EASTMAN KODAK COMPANY (US) | 1978-01-03 | — | — | US | disclosed |