Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345638 | 1.00 | DGKA (0.67) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL11329487 | 1.00 | DGKA (0.67) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL11336270 | 1.00 | DGKA (0.67) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10946046 | 0.98 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10945189 | 0.98 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10948667 | 0.98 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10946414 | 0.98 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10267034 | 0.95 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL6128364 | 0.95 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL16693727 | 0.93 | DGKA (0.55) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264576-A | SULFOALKYL ALKANOATE SALT IN SILICONE RUBBER AS UTERINE INSERT | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |