Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378119 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTFAAHKMT2AHPGD | |
| SCHEMBL7154654 | 0.75 | — | — | |
| SCHEMBL22508899 | 0.74 | EPHX2 (0.36) | EGLN1EPHX2MEN1KMT2AKCNA3 | |
| SCHEMBL14942867 | 0.72 | MAPT (0.39) | ALDH1A1MAPTTDP1LMNAMEN1 | |
| SCHEMBL19881354 | 0.72 | EPHX2 (0.44) | EGLN1ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL24666609 | 0.72 | EGLN1 (0.44) | EGLN1ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL4252185 | 0.72 | — | — | |
| SCHEMBL11406807 | 0.71 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11626673 | 0.70 | — | — | |
| SCHEMBL4198187 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346233-A | Process for the preparation of ureas | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | disclosed |