Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 6/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 6/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401080 | 0.96 | SCN1A (0.67) | SCN1ASCN2ASCN3ATSHRCYP3A4 | |
| SCHEMBL11340276 | 0.95 | TSHR (0.62) | SCN1ASCN2ASCN3ATSHRCYP3A4 | |
| SCHEMBL11339945 | 0.91 | ALDH1A1 (0.62) | SCN1ASCN2ASCN3ATSHRCYP3A4 | |
| SCHEMBL30173476 | 0.89 | TSHR (0.78) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL3805742 | 0.89 | TSHR (0.78) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL11341780 | 0.88 | TSHR (0.64) | SCN1ASCN2ASCN3ATSHRCYP3A4 | |
| SCHEMBL5515133 | 0.88 | ALDH1A1 (0.79) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL9636466 | 0.88 | ALDH1A1 (0.79) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL17961072 | 0.88 | ALDH1A1 (0.79) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL7078029 | 0.88 | ALDH1A1 (0.79) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298603-A | LOCAL ANESTHETICS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-11-03 | — | — | US | disclosed |
| EP-0031632-A1 | O-Aminoalkylsalicylates, process for their preparation, and their pharmaceutical compositions | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-07-08 | — | — | EP | disclosed |