Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412802 | 0.98 | PDE10A (0.50) | PDE10ALMNADHFRTLR8KCNH2 | |
| SCHEMBL11419112 | 0.98 | PDE10A (0.50) | PDE10ALMNADHFRTLR8KCNH2 | |
| SCHEMBL11328179 | 0.94 | PDE10A (0.53) | PDE10ALMNATLR8ALDH1A1MAPK1 | |
| SCHEMBL8518275 | 0.88 | TLR8 (0.50) | LMNADHFRTLR8KCNH2ALDH1A1 | |
| SCHEMBL7074713 | 0.86 | PDE10A (0.56) | PDE10ALMNAALDH1A1MAPK1 | |
| SCHEMBL27863633 | 0.86 | KCNH2 (0.53) | LMNADHFRTLR8KCNH2 | |
| SCHEMBL626394 | 0.86 | KCNH2 (0.53) | LMNADHFRTLR8KCNH2 | |
| SCHEMBL27905824 | 0.86 | KCNH2 (0.53) | LMNADHFRTLR8KCNH2 | |
| SCHEMBL18082979 | 0.82 | KDM4E (0.45) | PDE10ALMNADHFRTLR8KCNH2 | |
| SCHEMBL11337783 | 0.80 | MEN1 (0.42) | DHFRTLR8KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303689-A | Flavoring with pyrazine derivatives | FIRMENICH SA (CH) | 1981-12-01 | — | — | US | disclosed |
| US-4138410-A | Flavoring agent | FIRMENICH & CIE (CH) | 1979-02-06 | — | — | US | disclosed |
| US-4126618-A | FLAVOR ADDITIVES FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1978-11-21 | — | — | US | disclosed |
| US-4085109-A | Pyridine sulfur flavoring agents | FIRMENICH & CIE (CH) | 1978-04-18 | — | — | US | disclosed |
| US-3989713-A | Pyrrylmethylthio flavoring agents | FIRMENICH & CIE (CH) | 1976-11-02 | — | — | US | disclosed |
| US-3952024-A | FLAVOR ADDITIVE FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3943260-A | TETRAHYDRO-THIO-PHEN-3-ONES | FIRMENICH & CIE (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3931246-A | FURYLALKYL-THIOETHERS | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |