Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419112 | 1.00 | PDE10A (0.50) | PDE10ADHFRKCNH2TLR8LMNA | |
| SCHEMBL11345237 | 0.98 | PDE10A (0.51) | PDE10ADHFRKCNH2TLR8LMNA | |
| SCHEMBL11328179 | 0.93 | PDE10A (0.53) | PDE10ATLR8LMNATSHR | |
| SCHEMBL626394 | 0.89 | KCNH2 (0.53) | DHFRKCNH2TLR8LMNATSHR | |
| SCHEMBL27905824 | 0.89 | KCNH2 (0.53) | DHFRKCNH2TLR8LMNATSHR | |
| SCHEMBL27863633 | 0.89 | KCNH2 (0.53) | DHFRKCNH2TLR8LMNATSHR | |
| SCHEMBL8518275 | 0.87 | TLR8 (0.50) | DHFRKCNH2TLR8LMNATSHR | |
| SCHEMBL7074713 | 0.85 | PDE10A (0.56) | PDE10ALMNATSHR | |
| SCHEMBL18082979 | 0.83 | KDM4E (0.45) | PDE10ADHFRKCNH2TLR8LMNA | |
| SCHEMBL1550990 | 0.81 | KMT2A (0.46) | PDE10ADHFRKCNH2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228151-A | QUINOXALINE DIOXIDE | L'OREAL (FR) | 1980-10-14 | — | — | US | claimed |
| US-4228151-A | QUINOXALINE DIOXIDE | L'OREAL (FR) | 1980-10-14 | — | — | US | disclosed |