Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345575 | 0.86 | SMN1; SMN2 (0.64) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL1365207 | 0.79 | MAPT (0.71) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL6185460 | 0.79 | MAPT (0.52) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL10348407 | 0.79 | CACNA1B (0.44) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL8067143 | 0.78 | MAPT (0.57) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL9116289 | 0.77 | MAPT (0.56) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL10980033 | 0.76 | MAPT (0.61) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL4517861 | 0.75 | MAPT (0.55) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL31098224 | 0.75 | MAPT (0.62) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL8075179 | 0.75 | MAPT (0.62) | MAPTTDP1LMNAPOLBCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264769-A | BY REACTING A DIHYDROXYBENZENE WITH A HETEROCYCLIC OR PHENYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |