Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675484 | 0.85 | LMNA (0.54) | PPARGPPARDPPARALMNAMAPK14 | |
| SCHEMBL21992617 | 0.85 | LTA4H (0.49) | CACNA1BPPARGPPARDPPARALMNA | |
| SCHEMBL21991262 | 0.83 | ALDH1A1 (0.53) | PPARGPPARDPPARALMNAHTT | |
| SCHEMBL7747385 | 0.79 | HPGD (0.47) | CACNA1BLMNACACNA1HMAPK14HPGD | |
| SCHEMBL11345574 | 0.79 | MAPT (0.57) | PPARDLMNAHPGDKMT2AMAPT | |
| SCHEMBL21991845 | 0.76 | MAOB (0.63) | PPARGPPARAKMT2AMEN1 | |
| SCHEMBL8748928 | 0.76 | FFAR1 (0.54) | PPARGPPARDPPARALMNAKMT2A | |
| SCHEMBL28638978 | 0.75 | L3MBTL1 (0.52) | CACNA1BLMNATSHRMAPK14HPGD | |
| SCHEMBL9840493 | 0.74 | S1PR5 (0.47) | PPARGPPARDPPARALMNAMAPK14 | |
| SCHEMBL23606009 | 0.74 | ALDH1A1 (0.59) | CACNA1BPPARGPPARDPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163236-B1 | BENZOXAZOLYL AND BENZOTHIAZOLYL AMINOACIDS, THEIR PREPARATION AND THEIR USE IN THE PRESERVATION OF PLANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| US-4814459-A | REDUCING PHYTOTOXICITY OF HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |