Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455322 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7574189 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL11346583 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL30510955 | 0.95 | CA12 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14941064 | 0.95 | CA12 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5269925 | 0.90 | TDP1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7208677 | 0.90 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL30149754 | 0.90 | TDP1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7208685 | 0.90 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29543910 | 0.90 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000063-B1 | DIPEPTIDE DERIVATIVES OF 7-(N-ALPHA-SUBSTITUTED OR NON-SUBSTITUTED X-ARGINYL)-AMINO-4-METHYL-COUMARIN | AJINOMOTO CO., INC. (JP) | 1981-06-10 | — | — | EP | disclosed |
| US-4215047-A | FLUOROGENIC SUBSTRATES FOR DETERMINING ENZYMATIC ACTIVITIES | AJINOMOTO COMPANY INCORPORATED (JP) | 1980-07-29 | — | — | US | disclosed |
| EP-0000063-A1 | Dipeptide derivatives of 7-(N-alpha-substituted or non-substituted X-arginyl)-amino-4-methyl-coumarin | AJINOMOTO CO., INC. (JP) | 1978-12-20 | — | — | EP | disclosed |