Benzidine

Benzidine

SCHEMBL11345971

Nc1ccc(-c2ccc(N)cc2)cc1.[NaH]

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.92
ALDH1A1 P00352 7/20 0.92
TDP1 Q9NUW8 5/20 0.92
TP53 P04637 2/20 0.92
HSD17B10 Q99714 4/20 0.69
TAAR1 Q96RJ0 2/20 0.69
MAPT P10636 4/20 0.67
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
KIF11 P52732 1/20 0.55
APP P05067 2/20 0.53
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
CA14 Q9ULX7 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL29021 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL720393 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL5140469 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
SCHEMBL258287 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
SCHEMBL2024128 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
SCHEMBL28842081 0.96 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL25274606 0.92 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL6935192 0.92 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL9067542 0.92 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL22773196 0.92 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0013766-B1 ANTIBIOTICS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS PLANT PROTECTING AGENTS BAYER AG (DE) 1981-11-11 EP claimed
CN-111148520-B Use of composition comprising exosomes derived from adipose-derived stem cells as active ingredient for improving dermatitis 韩国外泌体生技有限公司 2023-10-10 CN disclosed