SCHEMBL258287

SCHEMBL258287

Nc1ccc(-c2ccc(-c3ccc(N)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 1.00
ALDH1A1 P00352 6/20 1.00
TDP1 Q9NUW8 5/20 1.00
TP53 P04637 2/20 1.00
HSD17B10 Q99714 3/20 0.73
TAAR1 Q96RJ0 2/20 0.73
MEN1 O00255 3/20 0.73
MAPT P10636 3/20 0.73
KMT2A Q03164 3/20 0.73
KIF11 P52732 1/20 0.58
APP P05067 2/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
CA14 Q9ULX7 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024128 1.00 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL5140469 1.00 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL720393 1.00 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL29021 1.00 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL25274606 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL6052806 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL11345971 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL9067542 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL22773196 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL570771 0.96 CYP3A4 (0.92) CYP3A4ALDH1A1TDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1893 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074082-A Polyimide film having improved breakdown characteristics and method for producing same 聚酰亚胺尖端素材株式会社 2026-05-22 CN claimed
CN-122037560-A Polyamic acid composition and polyimide prepared from same 聚酰亚胺尖端素材株式会社 2026-05-15 CN claimed
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
US-12534558-B2 Polymer terminated with polyaromatic hydrocarbon G-3 CHICKADEE PURCHASER, LLC (US) 2026-01-27 US claimed
US-12522704-B2 Polyimide film having high dimensional stability and manufacturing method therefor PI ADVANCED MATERIALS CO., LTD. (KR) 2026-01-13 US claimed
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR PL ADVANCED MAT CO LTD (KR) 2026-01-08 US claimed
US-12503596-B2 Low-dielectric-constant polyimide composite powder, and method for producing same PI ADVANCED MATERIALS CO., LTD. 2025-12-23 US claimed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US claimed
US-5252703-A Heat resistant, dielectric, flexibility UBE INDUSTRIES, LTD. (JP) 1993-10-12 US claimed
US-5241018-A Shaped articles for air- and spacecraft UBE INDUSTRIES, LTD. (JP) 1993-08-31 US claimed
EP-0540829-A1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-05-12 EP claimed
EP-0527439-A1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-02-17 EP claimed
EP-0459809-A1 Polyimidosiloxane resin and composition thereof and method of applying same UBE INDUSTRIES, LTD. (JP) 1991-12-04 EP claimed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US claimed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP claimed
US-4499252-A Process for producing polyimide precursor NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-02-12 US claimed
US-4137239-A MUSCLE RELAXANTS; REDUCTION, ALKYLATION KHROMOV BORISOV NIKOLAI V 1979-01-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PARG, PARN, DYNC1LI1 CYP3A4 3633/4885ALDH1A1 1618/4885TDP1 924/4885
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL CYP3A4 4110/4885ALDH1A1 3169/4885TDP1 1507/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 CYP3A4 3894/4885ALDH1A1 228/4885TDP1 1163/4885
US-12534558-B2 Polymer terminated with polyaromatic hydrocarbon POT1, TST, TELO2 CYP3A4 1175/4885ALDH1A1 1635/4885TDP1 142/4885
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR MALT1, CDH1, TET1 CYP3A4 2008/4885ALDH1A1 1801/4885TDP1 814/4885
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PARG, PARN, PUF60 CYP3A4 4409/4885ALDH1A1 1975/4885TDP1 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.