Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343003 | 0.85 | KMT2A (0.51) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2875550 | 0.83 | CA1 (0.50) | KMT2AALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL11344181 | 0.82 | KMT2A (0.44) | KMT2AALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL30735778 | 0.80 | SMN1; SMN2 (0.58) | KMT2AHSD17B10SMN1; SMN2PKMTSHR | |
| SCHEMBL940404 | 0.80 | SMN1; SMN2 (0.58) | KMT2AHSD17B10SMN1; SMN2PKMTSHR | |
| SCHEMBL5081102 | 0.79 | KMT2A (0.63) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10598079 | 0.78 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11886837 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1NSD2ESR1 | |
| SCHEMBL9548071 | 0.77 | PTGER4 (0.45) | SMN1; SMN2L3MBTL1LMNARAB9ANSD2 | |
| SCHEMBL11631620 | 0.76 | KMT2A (0.59) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001051-B1 | DERIVATIVES OF BENZENESULFONAMIDE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4235918-A | SALIDIURETICS, TREATMENT OF HYPERTONIC CONDITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |