Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940404 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL9548071 | 0.85 | PTGER4 (0.45) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL11893905 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL11886837 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL31401059 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL2782333 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL6293695 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL942239 | 0.81 | PKM (0.63) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 | |
| SCHEMBL669263 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1TDP1HSD17B10PKM | |
| SCHEMBL28614221 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1POLBTDP1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |