SCHEMBL1134819

SCHEMBL1134819

CCCCCCCCCCCCCCC(CCC(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.67
FFAR4 Q5NUL3 2/20 0.58
FFAR1 O14842 2/20 0.58
GRIK1 P39086 1/20 0.58
GRIK2 Q13002 1/20 0.58
GPR84 Q9NQS5 7/20 0.56
PPARG P37231 6/20 0.56
PPARD Q03181 6/20 0.56
PPARA Q07869 6/20 0.56
HDAC11 Q96DB2 5/20 0.56
TSHR P16473 4/20 0.56
ALDH1A1 P00352 2/20 0.56
TLR2 O60603 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
FABP4 P15090 2/20 0.56
PTPN1 P18031 2/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1506893 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL10765600 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL3619652 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL1506839 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL337545 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL338274 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL5596670 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL1134777 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL1506898 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2
SCHEMBL1506904 1.00 FOLH1 (0.67) FOLH1FFAR4FFAR1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112425581-A Production method of plant fiber trap and trap 湖北桔丰科技有限公司 2021-03-02 CN disclosed
US-8563488-B2 Functionalized polymer composition for grease THE LUBRIZOL CORPORATION (US) 2013-10-22 US disclosed
US-20110288052-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FAS SECURED CREDITORS HOLDCO, LLC 2011-11-24 US disclosed
EP-2386550-A1 Novel compounds, pharmaceutical compositions containing same, and methods of use for same Fasgen Inc. (US) 2011-11-16 EP disclosed
EP-2386551-A1 Novel compounds, pharmaceutical compositions containing same, and methods of use for same Fasgen Inc. (US) 2011-11-16 EP disclosed
US-D647106-S1 Display module for an electronic device APPLE INC. (US) 2011-10-18 US disclosed
US-8038089-B2 Leader member in recording tape cartridge, manufacturing method thereof, and recording tape cartridge FUJIFILM CORPORATION (JP) 2011-10-18 US disclosed
EP-2292721-A1 Functionalized polymer composition for grease The Lubrizol Corporation (US) 2011-03-09 EP disclosed
EP-2285215-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME Fasgen, Inc. (US) 2011-02-23 EP disclosed
US-20100168176-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FASGEN LLC (US) 2010-07-01 US disclosed
EP-0651636-B1 CHEMOTHERAPY FOR CANCER UNIV JOHNS HOPKINS (US) 2002-10-02 EP disclosed
EP-0738107-A4 INHIBITORS OF FATTY ACID SYNTHESIS AS ANTIMICROBIAL AGENTS UNIV JOHNS HOPKINS (US) 1998-09-09 EP disclosed
US-5759837-A ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS JOHN HOPKINS UNIVERSITY (US) 1998-06-02 US disclosed
US-5614551-A Inhibitors of fatty acid synthesis as antimicrobial agents THE JOHNS HOPKINS UNIVERSITY (US) 1997-03-25 US disclosed
EP-0738107-A1 INHIBITORS OF FATTY ACID SYNTHESIS AS ANTIMICROBIAL AGENTS THE JOHNS HOPKINS UNIVERSITY (US) 1996-10-23 EP disclosed
WO-1995019706-A1 INHIBITORS OF FATTY ACID SYNTHESIS AS ANTIMICROBIAL AGENTS THE JOHNS HOPKINS UNIVERSITY (US) 1995-07-27 WO disclosed
EP-0651636-A1 CHEMOTHERAPY FOR CANCER THE JOHNS HOPKINS UNIVERSITY (US) 1995-05-10 EP disclosed
WO-1994002108-A1 CHEMOTHERAPY FOR CANCER THE JOHNS HOPKINS UNIVERSITY (US) 1994-02-03 WO disclosed
US-4066587-A FLOWABILITY EMERY INDUSTRIES, INC. (US) 1978-01-03 US disclosed
US-4062819-A Polyamide blends having improved processing characteristics EMERY INDUSTRIES, INC. (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288052-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME C1S, C1R, MC2R FOLH1 2724/4885FFAR4 1555/4885FFAR1 871/4885
US-20100168176-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME AOC3, CYP2B6, CBR3 FOLH1 2484/4885FFAR4 527/4885FFAR1 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.