SCHEMBL11348229

SCHEMBL11348229

CCCNC(=O)c1ccccc1.[LiH]

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.71
POLB P06746 2/20 0.65
LMNA P02545 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.64
GAA P10253 1/20 0.61
DRD2 P14416 1/20 0.59
DRD4 P21917 1/20 0.59
DRD3 P35462 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
HDAC3 O15379 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
EPHX2 P34913 1/20 0.58
PRSS1 P07477 1/20 0.58
CTSG P08311 1/20 0.58
CTRB1 P17538 1/20 0.58
CMA1 P23946 1/20 0.58
HPGD P15428 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28248159 0.98 NAAA (0.73) NAAAPOLBLMNAL3MBTL1GAA
SCHEMBL334957 0.98 NAAA (0.73) NAAAPOLBLMNAL3MBTL1GAA
SCHEMBL11338329 0.96 NAAA (0.71) NAAAPOLBLMNAL3MBTL1GAA
Hydrochloric Acid SCHEMBL7763902 0.96 NAAA (0.71) NAAAPOLBLMNAL3MBTL1GAA
SCHEMBL11341368 0.96 NAAA (0.71) NAAAPOLBLMNAL3MBTL1GAA
Dimethylamine SCHEMBL15710136 0.94 NAAA (0.69) NAAAPOLBLMNAL3MBTL1GAA
Naphthalene SCHEMBL28863780 0.92 NAAA (0.67) NAAAPOLBLMNAL3MBTL1GAA
SCHEMBL17226037 0.91 NAAA (0.65) NAAAPOLBLMNAL3MBTL1GAA
Formic Acid SCHEMBL5398978 0.91 NAAA (0.65) NAAAPOLBLMNAL3MBTL1GAA
Fumaric Acid SCHEMBL5586485 0.89 NAAA (0.63) NAAAPOLBLMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436950-B Method for the alkylation of ester groups using lithium arylalkylamides as sterically bulky bases 凯莱英生命科学技术(天津)有限公司 2022-09-23 CN disclosed
CN-114436950-A Method for the alkylation of ester groups using lithium arylalkylamides as sterically bulky bases 凯莱英生命科学技术(天津)有限公司 2022-05-06 CN disclosed
US-4252977-A Novel acetamide compounds and process for producing them GENERAL ELECTRIC COMPANY (US) 1981-02-24 US disclosed