SCHEMBL11348346

SCHEMBL11348346

Clc1cccc(Cl)c1.O=[N+]([O-])c1cccc(Cl)c1

nearest known ligand 0.96

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.96
TDP1 Q9NUW8 1/20 0.96
TSHR P16473 5/20 0.67
LMNA P02545 3/20 0.67
ACHE P22303 1/20 0.55
ALOX15 P16050 1/20 0.55
HSP90AA1 P07900 1/20 0.53
HSD17B10 Q99714 1/20 0.52
GAA P10253 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
TP53 P04637 1/20 0.50
TRPV1 Q8NER1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249999 0.98 ALDH1A1 (1.00) ALDH1A1TDP1TSHRLMNAACHE
Ammonia Solution, Strong SCHEMBL27619132 0.96 ALDH1A1 (0.96) ALDH1A1TDP1TSHRLMNAACHE
Hydrogen Sulfide SCHEMBL28261652 0.96 ALDH1A1 (0.96) ALDH1A1TDP1TSHRLMNAACHE
Hydrochloric Acid SCHEMBL31522363 0.96 ALDH1A1 (0.96) ALDH1A1TDP1TSHRLMNAACHE
Dinitrophenylene SCHEMBL27804554 0.96 ALDH1A1 (0.88) ALDH1A1TDP1TSHRLMNAACHE
Hydrochloric Acid SCHEMBL28308368 0.94 ALDH1A1 (0.92) ALDH1A1TDP1TSHRLMNAACHE
Formaldehyde SCHEMBL28346696 0.94 ALDH1A1 (0.92) ALDH1A1TDP1TSHRLMNAACHE
Methylamine SCHEMBL11819382 0.92 ALDH1A1 (0.88) ALDH1A1TDP1TSHRLMNAACHE
SCHEMBL11603013 0.92 ALDH1A1 (0.88) ALDH1A1TDP1TSHRLMNAACHE
Nitrobenzene SCHEMBL11647692 0.92 ALDH1A1 (0.88) ALDH1A1TDP1TSHRLMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4306103-A Process for the manufacture of 1,3,5-trichlorobenzene HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed