SCHEMBL1134835

SCHEMBL1134835

Cc1nn(C)cc1C(=O)Nc1ccccc1-c1cc(F)c(F)cc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
CHRM3 P20309 1/20 0.48
NAMPT P43490 1/20 0.48
GAA P10253 5/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 1/20 0.46
EGFR P00533 1/20 0.45
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 2/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SSTR2 P30874 1/20 0.41
ALPL P05186 1/20 0.41
NTRK1 P04629 2/20 0.41
ATR Q13535 1/20 0.41
MAPT P10636 2/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445412 1.00 ATM (0.61) ATMCHRM3NAMPTGAARAB9A
SCHEMBL1085668 0.89 ATM (0.47) ATMCHRM3NAMPTGAARAB9A
SCHEMBL29445376 0.89 ATM (0.47) ATMCHRM3NAMPTGAARAB9A
SCHEMBL4456087 0.89 ATM (0.59) ATMCHRM3NAMPTGAARAB9A
SCHEMBL30917956 0.88 ATM (0.46) ATMCHRM3RAB9ASMN1; SMN2EGFR
SCHEMBL4450127 0.87 ATM (0.57) ATMCHRM3NAMPTGAARAB9A
SCHEMBL4920642 0.86 ATM (0.59) ATMCHRM3NAMPTGAARAB9A
SCHEMBL303117 0.86 CHRM3 (0.47) ATMCHRM3ALDH1A1MEN1KMT2A
SCHEMBL29445380 0.86 CHRM3 (0.47) ATMCHRM3ALDH1A1MEN1KMT2A
SCHEMBL21069152 0.86 ATM (0.58) ATMNAMPTGAARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
US-20150313235-A1 Method for Controlling Weeds Using Formulations Containing Fluthiacet-Methyl and HPPD Herbicides FMC CORP (US) 2015-11-05 US claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 EP claimed
US-8350046-B2 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-01-08 US claimed
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides BASF SE 2011-03-03 US claimed
EP-2285779-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2011-02-23 EP claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 US claimed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 US claimed
WO-2009135860-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2009-11-12 WO claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 ATM 3784/4885CHRM3 910/4885NAMPT 3602/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC ATM 1922/4885CHRM3 487/4885NAMPT 1815/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 ATM 3828/4885CHRM3 664/4885NAMPT 3310/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 ATM 1011/4885CHRM3 1239/4885NAMPT 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.