MYB

Transcriptional activator Myb · P10242 · MYB on Sugi Atlas →

1,047 patent compounds predicted against MYB, 670 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL14478940 SCHEMBL14478940 0.73 19/20
SCHEMBL4335346 SCHEMBL4335346 1.00 18/20
SCHEMBL20368759 SCHEMBL20368759 0.90 18/20
SCHEMBL5044963 SCHEMBL5044963 0.89 18/20
SCHEMBL4327922 SCHEMBL4327922 0.83 18/20
SCHEMBL4325696 SCHEMBL4325696 0.78 18/20
SCHEMBL12136727 SCHEMBL12136727 0.75 18/20
SCHEMBL20368770 SCHEMBL20368770 0.72 18/20
SCHEMBL8808882 SCHEMBL8808882 0.58 18/20
SCHEMBL8539407 SCHEMBL8539407 0.58 18/20
SCHEMBL8539876 SCHEMBL8539876 0.56 18/20
SCHEMBL8539879 SCHEMBL8539879 0.56 18/20
SCHEMBL8543671 SCHEMBL8543671 1.00 17/20
SCHEMBL15614738 SCHEMBL15614738 1.00 17/20
SCHEMBL6014204 SCHEMBL6014204 0.89 17/20
SCHEMBL5048163 SCHEMBL5048163 0.89 17/20
SCHEMBL4331540 SCHEMBL4331540 0.87 17/20
SCHEMBL4534455 SCHEMBL4534455 0.83 17/20
SCHEMBL8538963 SCHEMBL8538963 0.80 17/20
SCHEMBL5044967 SCHEMBL5044967 0.59 17/20

Clinical trials — most relevant to MYB by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population PHASE2ACTIVE_NOT_RECRUITING
Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients PHASE2COMPLETED
Stem Cell Monitoring for CML Patients Undergoing Nilotinib Therapy PHASE2COMPLETED
Metformin for Fibromyalgia Symptoms (INFORM Trial) PHASE2RECRUITING
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial) PHASE2RECRUITING
A Study to Evaluate Efficacy & Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Richter's Syndrome; PHASE2COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) PHASE1COMPLETED
Obinutuzumab in Combination With Venetoclax in Previously Untreated Follicular Lymphoma Patients PHASE1COMPLETED
MicroRNA-150 and microRNA-155 in Multiple Sclerosis nanUNKNOWN
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Aberrant Expression of Micro RNA for Diagnosis of Breast Cancer nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors nanUNKNOWN
Immune Interactions in Severe Asthma nanCOMPLETED
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea nanRECRUITING
Timisnar - Biomarkers Substudy (Timisnar-mirna) nanUNKNOWN
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome nanCOMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Study for the Multidimensional Analyses of Resistance and Toxicity to Immune- and Targeted-therapies. nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
The Role of TBX3 in Human ES Cell Differentiation nanWITHDRAWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis nanCOMPLETED
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Involvement of Pollutants in Atopic Dermatitis and Psoriasis nanUNKNOWN
Role of Vitamin C Infusion in Postoperative Mechanically Ventilated Neonates With Sepsis nanCOMPLETED
Vascular Endothelial Factor Gene Polymorphism in Preeclampsia nanCOMPLETED
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MYB binder may also engage these)

ProteinNameSimilarity
P46200 1.000 P46200 →
P01103 1.000 P01103 →
P10244 1.000 P10244 →
P06876 1.000 P06876 →
P52550 0.998 P52550 →
Q05935 0.997 Q05935 →
Q90655 0.997 Q90655 →
Q03237 0.996 Q03237 →
P70284 0.996 P70284 →
Q949U2 0.995 Q949U2 →
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 0.994 landscape →
Q3YC04 0.994 Q3YC04 →
Q29131 0.994 Q29131 →
Q90ZS6 0.994 Q90ZS6 →
P52551 0.994 P52551 →
Q8VII8 0.994 Q8VII8 →
P48972 0.994 P48972 →
O43310 0.993 O43310 →
Q4JM28 0.993 Q4JM28 →
Q08759 0.993 Q08759 →
P06536 0.993 P06536 →
Q0P4H6 0.993 Q0P4H6 →
P06537 0.993 P06537 →
Q5WM45 0.993 Q5WM45 →
P22199 0.993 P22199 →
BMP2K BMP-2-inducible protein kinase 0.993 landscape →
A7MBB4 0.992 A7MBB4 →
Q0JHU7 0.992 Q0JHU7 →
Q8R4I4 0.992 Q8R4I4 →
Q6YXZ4 0.992 Q6YXZ4 →