Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | USP8 | P40818 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 2/20 | 0.36 |
| ▸ | POR | P16435 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346081 | 0.83 | NQO1 (0.33) | MAOBRAB9AMAPTSMN1; SMN2NQO1 | |
| SCHEMBL11345791 | 0.81 | NQO1 (0.33) | NQO1POR | |
| SCHEMBL11345788 | 0.81 | NQO1 (0.33) | NQO1POR | |
| SCHEMBL11353687 | 0.81 | USP8 (0.44) | MAOBUSP8USP7RAB9AMAPT | |
| SCHEMBL11352822 | 0.80 | USP8 (0.48) | MAOAMAOBUSP8RAB9AMAPT | |
| SCHEMBL11020695 | 0.79 | POLB (0.52) | MAOAUSP8USP7RAB9AMAPT | |
| SCHEMBL24976667 | 0.75 | ELANE (0.42) | MAOBELANEUSP8USP7RAB9A | |
| SCHEMBL24976533 | 0.75 | ELANE (0.42) | MAOBELANEUSP8USP7RAB9A | |
| SCHEMBL11359550 | 0.73 | TDP2 (0.50) | ELANEUSP8USP7RAB9ASMN1; SMN2 | |
| SCHEMBL583153 | 0.72 | ELANE (0.86) | MAOAMAOBELANEUSP8USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002310-A1 | 4,9-Dihydro-4,9-dioxo-1H-naphtho(2,3-d) triazoles, their preparation and antiallergic compositions containing them | BEECHAM GROUP PLC (GB) | 1979-06-13 | — | — | EP | claimed |
| EP-0002310-B1 | 4,9-DIHYDRO-4,9-DIOXO-1H-NAPHTHO(2,3-D) TRIAZOLES, THEIR PREPARATION AND ANTIALLERGIC COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1981-06-24 | — | — | EP | disclosed |
| US-4263309-A | ASTHMA, HAY FEVER, RHINITIS | BEECHAM GROUP LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0002310-A1 | 4,9-Dihydro-4,9-dioxo-1H-naphtho(2,3-d) triazoles, their preparation and antiallergic compositions containing them | BEECHAM GROUP PLC (GB) | 1979-06-13 | — | — | EP | disclosed |