Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437894 | 0.98 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2AAPP | |
| SCHEMBL8384077 | 0.98 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2AAPP | |
| SCHEMBL8532305 | 0.98 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AAPP | |
| SCHEMBL8529768 | 0.96 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AAPP | |
| SCHEMBL16589837 | 0.91 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AAPP | |
| SCHEMBL421993 | 0.90 | APP (0.50) | TSHRAPPHTTMAPTALDH1A1 | |
| SCHEMBL25299218 | 0.87 | APP (0.48) | TSHRMEN1KMT2AAPPHTT | |
| SCHEMBL22160261 | 0.87 | APP (0.48) | TSHRMEN1KMT2AAPPHTT | |
| SCHEMBL20875302 | 0.87 | APP (0.48) | APPLMNABLMPTGS1PDE4A | |
| SCHEMBL4731267 | 0.87 | APP (0.48) | APPLMNABLMPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307185-A | SENSITIZING DYE OF CYANINE STRUCTURE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
| US-4040840-A | MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |
| US-4028112-A | MEROCYANINE DYE WITH OXAZOLE NUCLEUS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |