SCHEMBL22160261

SCHEMBL22160261

O=S(=O)(O)CCCOCCOCCCS(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25299218 1.00 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL421993 0.97 APP (0.50) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL4731267 0.94 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL20875302 0.94 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL2191721 0.94 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL19640302 0.94 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL263732 0.92 APP (0.46) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL18380848 0.92 APP (0.46) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL8384077 0.91 MEN1 (0.50) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL29437894 0.91 MEN1 (0.50) APPPTGS1PDE4ALMNASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118086987-A Copper electroplating solution and preparation method thereof 苏州捷得宝机电设备有限公司 2024-05-28 CN disclosed
US-20200207744-A1 DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA EXPANSION THERAPEUTICS, INC. 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200207744-A1 DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA HNRNPH1, HNRNPUL2, HNRNPH3 APP 2211/4885PTGS1 4429/4885PDE4A 4343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.