Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.57 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518479 | 0.93 | L3MBTL1 (0.58) | CA1CA2MMENAALAD2ACE | |
| SCHEMBL29619848 | 0.93 | L3MBTL1 (0.58) | CA1CA2MMENAALAD2ACE | |
| SCHEMBL3497457 | 0.93 | L3MBTL1 (0.58) | CA1CA2MMENAALAD2ACE | |
| SCHEMBL11119910 | 0.90 | CA1 (0.56) | ITGB1ITGA4ITGB7CA1CA2 | |
| SCHEMBL6800452 | 0.89 | ITGB1 (0.57) | ITGB1ITGA4ITGB7CA1CA2 | |
| SCHEMBL11122142 | 0.86 | CA1 (0.57) | ITGB1ITGA4ITGB7CA1CA2 | |
| SCHEMBL11122263 | 0.86 | CA1 (0.57) | ITGB1ITGA4ITGB7CA1CA2 | |
| SCHEMBL3975655 | 0.85 | KDR (0.62) | KDM4EALDH1A1LMNATSHRELANE | |
| SCHEMBL3975653 | 0.85 | KDR (0.62) | KDM4EALDH1A1LMNATSHRELANE | |
| SCHEMBL7648431 | 0.84 | ELANE (0.59) | ITGB1ITGA4ITGB7MMENHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302448-A | Secretin preparations with intensified and protracted action, process for their manufacture, their use as well as dihydroxybenzoyl-L-tyrosine | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |