Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346035 | 0.86 | LMNA (0.48) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11379562 | 0.85 | LMNA (0.50) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11345737 | 0.84 | LMNA (0.51) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11341345 | 0.83 | LMNA (0.50) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11344784 | 0.83 | LMNA (0.50) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11339698 | 0.82 | LMNA (0.49) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11541112 | 0.82 | SCN5A (0.53) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11343456 | 0.81 | LMNA (0.48) | LMNASCN5ACNR1CYP1A2MAOA | |
| Hydrochloric Acid SCHEMBL11345886 | 0.81 | LMNA (0.50) | LMNASCN5ACNR1CYP1A2MAOA | |
| SCHEMBL11351301 | 0.81 | LMNA (0.48) | LMNASCN5ACNR1CYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272546-A | ANTILIPEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4254138-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4196208-A | ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |