Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165788 | 0.83 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL11357003 | 0.82 | TAS1R3 (0.42) | FFAR1TAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL11347913 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL11348524 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL31135381 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL20969576 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL801219 | 0.76 | HDAC4 (0.48) | SLC6A2SLC6A4SLC6A3AKR1C3AKR1C2 | |
| SCHEMBL13304652 | 0.76 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL25620264 | 0.76 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3FFAR1CYP3A4 | |
| SCHEMBL25620269 | 0.75 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3FFAR1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |