Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346033 | 0.91 | NPC1 (0.38) | NPC1RAB9ADHFRHSPA5LMNA | |
| SCHEMBL3077803 | 0.90 | HSPA5 (0.42) | NPC1RAB9AHSPA5LMNAGAA | |
| SCHEMBL11420200 | 0.90 | HSPA5 (0.43) | NPC1RAB9ADHFRHSPA5LMNA | |
| SCHEMBL14323973 | 0.89 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL699155 | 0.89 | NPC1 (0.47) | NPC1RAB9AHSPA5LMNAPOLB | |
| SCHEMBL11348047 | 0.88 | NPC1 (0.52) | NPC1RAB9ADHFRHSPA5LMNA | |
| SCHEMBL3076020 | 0.86 | HSPA5 (0.55) | NPC1RAB9AHSPA5LMNAGAA | |
| SCHEMBL11340054 | 0.86 | NPC1 (0.50) | NPC1RAB9ADHFRHSPA5LMNA | |
| SCHEMBL11338684 | 0.86 | NPC1 (0.39) | NPC1RAB9ADHFRHSPA5LMNA | |
| SCHEMBL11345959 | 0.86 | NPC1 (0.40) | NPC1RAB9ADHFRHSPA5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031302-A2 | Benzotriazole UV absorbers, process for their preparation and stabilized mixtures | CIBA-GEIGY AG (CH) | 1981-07-01 | — | — | EP | disclosed |