Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495521 | 0.83 | TYR (0.56) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL27880027 | 0.83 | TYR (0.56) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL816624 | 0.83 | TYR (0.56) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL379742 | 0.77 | TYR (0.57) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL107304 | 0.76 | TYR (0.51) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL9074096 | 0.76 | TYR (0.50) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL688631 | 0.75 | BID (0.56) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL11582639 | 0.75 | BID (0.56) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL9619227 | 0.74 | MAPT (0.43) | MEN1CYP3A4MAPTHTTKMT2A | |
| SCHEMBL9324343 | 0.72 | CNR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003479-B1 | HARDENING AGENTS AND PROCESS FOR PREPARING EPOXY RESIN POLYADDUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4269742-A | REACTING AN EPOXY COMPOUND WITH A LIQUID AMINE PREPARED BY REACTING A MANNICH BASE WITH A AMINO-AMIDE WITH OR WITHOUT AN IMIDAZOLINE RING, OR A POLYAMINE; LOW TEMPERATURE | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-05-26 | — | — | US | disclosed |
| EP-0003479-A1 | Hardening agents and process for preparing epoxy resin polyadducts | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-08-22 | — | — | EP | disclosed |