Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506307 | 0.94 | TYR (0.46) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL27880027 | 0.85 | TYR (0.56) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL11495521 | 0.85 | TYR (0.56) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL816624 | 0.85 | TYR (0.56) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1861164 | 0.80 | ESR1 (0.39) | ALOX15TDP1ESR1TRPV1ALDH1A1 | |
| SCHEMBL9074096 | 0.78 | TYR (0.50) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL688631 | 0.78 | BID (0.56) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1001383 | 0.76 | KLF10 (0.43) | TYRALOX15TSHRHTTTDP1 | |
| SCHEMBL11352199 | 0.76 | TYR (0.53) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL379742 | 0.76 | TYR (0.57) | TYRTP53CYP3A4MEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424738-A1 | TIRE WITH CONTROLLED RESISTANCE TO THE FORMATION OF SURFACE DEFECTS | Pirelli Tyre S.P.A. (IT) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124977-A1 | TIRE WITH CONTROLLED RESISTANCE TO THE FORMATION OF SURFACE DEFECTS | PIRELLI TYRE S.P.A. (IT) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010108857-A1 | STABILISED COMPOSITIONS COMPRISING OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-09-30 | — | — | WO | disclosed |