SCHEMBL11352802

SCHEMBL11352802

CN(C)CCOC(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.67
ALDH1A1 P00352 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
MAPT P10636 1/20 0.60
LMNA P02545 3/20 0.57
TDP1 Q9NUW8 2/20 0.56
GAA P10253 1/20 0.55
CYP1A2 P05177 1/20 0.55
MAOA P21397 1/20 0.55
CNR1 P21554 1/20 0.55
DRD4 P21917 1/20 0.55
ACHE P22303 1/20 0.55
HRH2 P25021 1/20 0.55
HTR2A P28223 1/20 0.55
HTR2C P28335 1/20 0.55
MAPK1 P28482 1/20 0.55
NTSR1 P30989 1/20 0.55
HRH1 P35367 1/20 0.55
DRD3 P35462 1/20 0.55
SCN1A P35498 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65544 0.93 PHLPP2 (0.70) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL11358749 0.91 GAA (0.68) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL8963488 0.88 PHLPP2 (0.83) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL28225097 0.84 SMN1; SMN2 (0.61) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL11239419 0.84 TDP1 (0.70) ALDH1A1SMN1; SMN2LMNATDP1GAA
Benzophenone SCHEMBL30485144 0.83 HPGD (0.59) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL11287086 0.83 GAA (0.71) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL31243763 0.83 ALDH1A1 (0.59) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL11650559 0.82 GAA (0.58) PHLPP2ALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL8055450 0.82 TDP1 (0.73) PHLPP2ALDH1A1SMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US claimed
EP-0000705-B1 USE OF ESTERS OR AMIDES OF BENZOYLBENZOIC ACIDS AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE COMPOSITION CONTAINING THEM STAUFFER CHEMICAL COMPANY (US) 1981-02-11 EP disclosed
EP-0000705-A1 Use of esters or amides of benzoylbenzoic acids as photoinitiators and photopolymerisable composition containing them STAUFFER CHEMICAL COMPANY (US) 1979-02-21 EP disclosed
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US disclosed