Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTGFR | P43088 | 2/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353581 | 1.00 | CA1 (0.47) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL311165 | 0.83 | NFKB1 (0.61) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL27735189 | 0.83 | NFKB1 (0.61) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL28782162 | 0.82 | CA1 (0.47) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL11354269 | 0.82 | CA1 (0.46) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL11354273 | 0.82 | CA1 (0.46) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL21462333 | 0.82 | CA1 (0.46) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL1535400 | 0.82 | CA1 (0.46) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL4287188 | 0.80 | PTGER3 (0.50) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL1451542 | 0.80 | PTGER3 (0.50) | CA1CA2NFKB1CA4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244966-A | 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |