Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124601 | 0.86 | TYR (0.39) | TYRKDM4EALDH1A1SMN1; SMN2MME | |
| SCHEMBL6443625 | 0.83 | TYR (0.41) | CAPN1TYRALDH1A1SMN1; SMN2MME | |
| SCHEMBL6443853 | 0.83 | TYR (0.41) | CAPN1TYRALDH1A1SMN1; SMN2MME | |
| SCHEMBL3838151 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 | |
| SCHEMBL21458084 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 | |
| SCHEMBL21457984 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 | |
| SCHEMBL13417072 | 0.82 | TYR (0.39) | CAPN1TYRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3843124 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 | |
| SCHEMBL3843983 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 | |
| SCHEMBL3837516 | 0.82 | ALDH1A1 (0.50) | CAPN1TYRALDH1A1MMEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012957-B1 | DIAGNOSTIC MEANS FOR THE DETECTION OF PROTEOLYTIC ENZYMES AND INDOXYL OR THIOINDOXYL ESTER CHROMOGENS USEFUL THEREFOR, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF DIAGNOSTIC MEANS | Roche Diagnostics GmbH (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4278763-A | Diagnostic agents for the detection of proteolytic enzymes | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0012957-A1 | Diagnostic means for the detection of proteolytic enzymes and indoxyl or thioindoxyl ester chromogens useful therefor, process for their preparation and their use in the preparation of diagnostic means | Roche Diagnostics GmbH (DE) | 1980-07-09 | — | — | EP | disclosed |