Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10257637 | 0.77 | CYP2D6 (0.44) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL12555585 | 0.77 | CYP2D6 (0.44) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL5611768 | 0.76 | CYP2C19 (0.36) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL8923168 | 0.73 | LMNA (0.44) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL10456585 | 0.73 | CYP2C19 (0.34) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL17616783 | 0.73 | CYP2C19 (0.34) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL8105843 | 0.73 | HCAR2 (0.43) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL28650756 | 0.73 | TSHR (0.44) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL291361 | 0.73 | HCAR2 (0.43) | TSHRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL19305342 | 0.72 | CYP2C19 (0.47) | ALDH1A1CYP2C19LMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306083-A | Multiphase oxidation of alcohol to aldehyde | THE DOW CHEMICAL COMPANY (US) | 1981-12-15 | — | — | US | disclosed |