Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380049 | 0.88 | THRA (0.64) | THRATHRBESR1SMPD1PTPN11 | |
| SCHEMBL26926530 | 0.88 | THRA (0.64) | THRATHRBESR1SMPD1PTPN11 | |
| SCHEMBL1201551 | 0.87 | SMPD1 (0.58) | THRATHRBESR1SMPD1PTPN11 | |
| SCHEMBL12603169 | 0.87 | ESR1 (0.72) | THRATHRBESR1KDM4EMEN1 | |
| SCHEMBL1199891 | 0.86 | SMPD1 (0.56) | THRATHRBSMPD1ALDH1A1HPGD | |
| SCHEMBL11436573 | 0.86 | THRA (0.68) | THRATHRBSMPD1PTPN11ALDH1A1 | |
| SCHEMBL26926728 | 0.86 | THRA (0.68) | THRATHRBSMPD1PTPN11ALDH1A1 | |
| SCHEMBL9638859 | 0.86 | THRA (0.68) | THRATHRBSMPD1PTPN11ALDH1A1 | |
| SCHEMBL11340705 | 0.85 | CA12 (0.59) | ESR1SMPD1ALDH1A1HPGDNPC1 | |
| SCHEMBL18077316 | 0.85 | CA12 (0.48) | THRATHRBESR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251545-A | Fungicidal process using 1-(alkoxyaroyl)guanidines | GAF CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |