Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490158 | 0.85 | ACE (0.66) | ACEKMT2A | |
| SCHEMBL11502463 | 0.85 | ACE (0.66) | ACEKMT2A | |
| SCHEMBL10974472 | 0.85 | ACE (0.66) | ACEKMT2A | |
| SCHEMBL11458690 | 0.85 | ACE (0.48) | ACEKMT2A | |
| SCHEMBL11458689 | 0.85 | ACE (0.48) | ACEKMT2A | |
| SCHEMBL7377578 | 0.78 | PEPD (0.48) | ACEHSD17B10 | |
| SCHEMBL11155540 | 0.78 | ACE (0.49) | ACENPSR1HSD17B10 | |
| SCHEMBL11390755 | 0.78 | ACE (0.53) | ACE | |
| SCHEMBL11223697 | 0.78 | ACE (0.47) | ACENPSR1HSD17B10 | |
| SCHEMBL11164632 | 0.77 | ACE (0.48) | ACENPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283407-A | ANTIHYPERTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-08-11 | — | — | US | disclosed |