Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355277 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL11355283 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL11355774 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL11355796 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL9756787 | 0.88 | LMNA (0.38) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL9756788 | 0.88 | LMNA (0.38) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL17662480 | 0.87 | MEN1 (0.45) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL17662477 | 0.87 | MEN1 (0.45) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL14672112 | 0.87 | MEN1 (0.40) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL8865823 | 0.87 | MEN1 (0.40) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305876-A | CULTURE PRODUCT INTERMEDIATE IN THE PREPARATION OF VITAMINS E AND K | HOFFMANN-LA ROCHE, INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4138289-A | ASYMMETRIC HYDROGENATION BY MICROORGANISM, FERMENTATION | HOFFMANN-LA ROCHE INC. (US) | 1979-02-06 | — | — | US | disclosed |