Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354598 | 0.87 | HRH4 (0.40) | HRH4HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11389974 | 0.86 | IDO1 (0.40) | IDO1HRH4HRH3CARM1PRMT6 | |
| SCHEMBL11350991 | 0.86 | IDO1 (0.40) | IDO1HRH4HRH3CARM1PRMT6 | |
| SCHEMBL11349907 | 0.83 | IDO1 (0.40) | IDO1HRH4HRH3CARM1PRMT6 | |
| SCHEMBL11361522 | 0.83 | KDM4E (0.44) | IDO1HRH4HRH3CARM1PRMT6 | |
| SCHEMBL11348628 | 0.83 | IDO1 (0.40) | IDO1HRH4HRH3CARM1PRMT6 | |
| SCHEMBL11353501 | 0.79 | HRH4 (0.56) | HRH4HRH3POLBTSHRL3MBTL1 | |
| SCHEMBL11352847 | 0.77 | HRH4 (0.42) | HRH4HRH3 | |
| SCHEMBL11349084 | 0.75 | KMT2A (0.57) | IDO1PKMKMT2ATSHRRAB9A | |
| SCHEMBL11352168 | 0.72 | IDO1 (0.45) | IDO1CARM1PRMT6SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000002-B1 | TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000002-A1 | Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |