Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355282 | 0.87 | IDO1 (0.40) | HRH4HRH3ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL11361522 | 0.87 | KDM4E (0.44) | HRH4HRH3ALDH1A1CYP2A13MAOB | |
| SCHEMBL11348628 | 0.87 | IDO1 (0.40) | HRH4HRH3TACR1ALDH1A1CYP2A13 | |
| SCHEMBL11393626 | 0.84 | HRH4 (0.38) | HRH4HRH3ACHEGBA1ADRA2A | |
| SCHEMBL11353120 | 0.84 | HRH4 (0.38) | HRH4HRH3ACHEGBA1ADRA2A | |
| SCHEMBL11359208 | 0.83 | HRH4 (0.37) | HRH4HRH3ACHEGBA1ADRA2A | |
| SCHEMBL11353501 | 0.83 | HRH4 (0.56) | HRH4HRH3ACHETAAR1 | |
| SCHEMBL28407405 | 0.78 | ALDH1A1 (0.56) | ACHEADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL11360900 | 0.76 | HRH4 (0.36) | HRH4HRH3ALDH1A1GLACYP2A13 | |
| SCHEMBL19407776 | 0.76 | KDM4E (0.47) | CYP2A13SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000002-B1 | TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000002-A1 | Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |