SCHEMBL11355992

SCHEMBL11355992

CCCCCCCCCCCC/C1=N\CCCCCCCCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2D6 P10635 1/20 0.39
ACHE P22303 2/20 0.38
BACE1 P56817 1/20 0.38
CCR5 P51681 2/20 0.36
NOS3 P29474 3/20 0.34
NOS1 P29475 3/20 0.34
NOS2 P35228 3/20 0.34
ALDH1A1 P00352 2/20 0.34
SPHK1 Q9NYA1 1/20 0.34
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015557 0.92 CYP2D6 (0.41) MEN1KMT2ACYP2D6NOS3NOS1
SCHEMBL3659904 0.90 MEN1 (0.38) MEN1KMT2ACYP2D6ACHEBACE1
Fluoride SCHEMBL29252750 0.88 MEN1 (0.37) MEN1KMT2ACYP2D6ACHEBACE1
SCHEMBL8907882 0.84
SCHEMBL1760704 0.81
SCHEMBL8412913 0.81 NOS3 (0.39) MEN1KMT2ANOS3NOS1NOS2
SCHEMBL24756802 0.74 NOS3 (0.42) MEN1KMT2ACYP2D6NOS3NOS1
SCHEMBL15919221 0.74
SCHEMBL13742940 0.74 NOS3 (0.42) MEN1KMT2ACYP2D6NOS3NOS1
SCHEMBL12020351 0.74 NOS3 (0.42) MEN1KMT2ACYP2D6NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0027194-A1 Process for producing sodium bicarbonate and hydrogen chloride CHEMISCHE WERKE HÜLS AG (DE) 1981-04-22 EP disclosed