Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775413 | 0.82 | SLC6A2 (0.47) | MEN1KMT2AMAPK1ALDH1A1CYP2D6 | |
| SCHEMBL10891239 | 0.79 | CASP3 (0.55) | CASP3MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL6359887 | 0.78 | TSHR (0.50) | MAPTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL14081825 | 0.78 | TSHR (0.50) | MAPTSMN1; SMN2LMNAALDH1A1NPC1 | |
| Propham SCHEMBL67344 | 0.77 | SMN1; SMN2 (0.66) | CASP3MEN1KMT2AMAPTEPHX2 | |
| Propham SCHEMBL8536412 | 0.77 | SMN1; SMN2 (0.66) | CASP3MEN1KMT2AMAPTEPHX2 | |
| Propham SCHEMBL28077800 | 0.75 | SMN1; SMN2 (0.64) | CASP3MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL11358778 | 0.75 | SMN1; SMN2 (0.50) | CASP3MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL910267 | 0.74 | CASP3 (0.53) | CASP3MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL1032817 | 0.74 | CASP3 (0.53) | CASP3MEN1KMT2AMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252716-A | BLUE SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |